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Ap44mSe

Selenosemicarbazone

Ap44mSe is a selenosemicarbazone compound that targets cellular iron metabolism. It effectively depletes cellular iron levels, leading to the up-regulation of transferrin receptor-1, down-regulation of ferritin, and increased expression of the metastasis suppressor N-myc downstream regulated gene-1. Additionally, Ap44mSe forms redox-active copper complexes that target lysosomes, inducing lysosomal membrane permeabilization, which may have significant implications for cancer research and therapy.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	79514-49-1
Applications	Selenosemicarbazone
Formula	C₁₀H₁₄N₄Se
Molecular Weight	269.20
SMILES	C/C(C1=NC=CC=C1)=N\NC(N(C)C)=[Se]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.