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Ap4dT tetraammonium

hAK1 Inhibitor

Ap4dT tetraammonium is a selective inhibitor of human adenylate kinase isozyme 1 (hAK1). This compound effectively inhibits ATP and ADP synthesis, demonstrating IC50 values of 42 μM and 38 μM, respectively. It is valuable for research into metabolic regulation and cellular energy homeostasis, enabling studies on the role of hAK1 in various physiological and pathological conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1146545-74-5
Applications	hAK1 Inhibitor
Formula	C₂₀H₄₁N₁₁O₂₀P₄
Molecular Weight	879.50
SMILES	O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(OP(OC[C@@H](O2)[C@@H](O)C[C@@H]2N3C(NC(C(C)=C3)=O)=O)(O)=O)(O)=O)(O)=O)(O)=O)O[C@H]1N4C5=NC=NC(N)=C5N=C4.N.N.N.N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.