Apatinib

Catalog No.: A17249

tyrosine kinase inhibitor

Apatinib

Apatinib Chemical Structure

CAS NO. 1218779-75-9

Apatinib (YN968D1) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 with an IC50 of 1 nM.

Availability: In stock

Package Price Qty
5 mg
$119.00
10 mg
$205.00
50 mg
$607.00
100 mg
$1,214.00
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Biological Activity

Apatinib (YN968D1) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 with an IC50 of 1 nM.
In vitro (25°C) DMSO 20 mg/mL (40.52 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.26 mL 101.3 mL 202.6 mL
0.5 mM 4.05 mL 20.26 mL 40.52 mL
1 mM 2.03 mL 10.13 mL 20.26 mL
5 mM 0.41 mL 2.03 mL 4.05 mL

*The above data is based on the productmolecular weight 493.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17249
Actions Inhibitor
CAS No. 1218779-75-9
Formula C25H27N5O4S
M. Wt 493.58
Purity >98%
Synonyms YN968D1
SMILES O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC=C(C4(C#N)CCCC4)C=C3.CS(=O)(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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