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APC8696

Catalog No.: A76987
uPA Inhibitor
APC8696 is a reversible inhibitor of urokinase-type plasminogen activator (uPA), exhibiting a nanomolar inhibitory constant (Ki) of 8 nM. This compound is valuable for investigating uPA-mediated processes in various biological systems. It is particularly relevant in cancer research and studies addressing tissue remodeling and inflammation.
APC8696 277312-42-2 uPA Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAPC8696 is a reversible inhibitor of urokinase-type plasminogen activator (uPA), exhibiting a nanomolar inhibitory constant (Ki) of 8 nM. This compound is valuable for investigating uPA-mediated processes in various biological systems. It is particularly relevant in cancer research and studies addressing tissue remodeling and inflammation.
Product Information
Catalog NumA76987
FormulaC21H17N3O
Molecular Weight327.38
CAS Number277312-42-2
SMILESN=C(C1=CC=C2NC(C3=CC=CC(C4=CC=CC=C4)=C3O)=CC2=C1)N
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Proteases > Urokinase