Fig. 1 · Structure
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Apelin-13
APJ Endogenous Ligand
Apelin-13 is an endogenous ligand for the G-protein coupled receptor APJ, exhibiting potent activation with an EC50 value of 0.37 nM. This peptide plays a significant role in cardiovascular regulation through its vasodilatory and antihypertensive effects. Additionally, Apelin-13 is a valuable tool for research into type 2 diabetes and metabolic syndrome, as it is widely distributed in both central and peripheral nervous systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 217082-58-1 |
| Applications | APJ Endogenous Ligand |
| Formula | C69H111N23O16S |
| Molecular Weight | 1550.83 |
| SMILES | C([C@@H](NC(=O)[C@H]1N(C(CNC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@H](CCC(N)=O)N)=O)CCCNC(=N)N)=O)CCC3)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)=O)CCCCN)=O)=O)CCC1)CCSC)(=O)N4[C@H](C(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)CCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.