API-1

Name: API-1
Brand: Adooq Bioscience
SKU: A22093
Rating: 5 (288 reviews)

Catalog No.: A22093

Akt inhibitor

API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis.

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Grouped product items
Size	Price	Stock
1mg	$70.00	In stock
5mg	$150.00	In stock
10mg	$255.00	In stock
25mg	$425.00	In stock
50mg	$585.00	In stock
100mg	$820.00	In stock
200mg	$1,085.00	In stock
*10mM 1mL in DMSO**	$170.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis.

Product Information

Catalog Num	A22093
Formula	C13H15N5O6
Molecular Weight	337.29
CAS Number	36707-00-3
SMILES	O=C(C1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=NC=NC(N)=C3C1=O)N
Synonyms	API1; API 1; NSC177233.
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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