Fig. 1 · Structure
Documents & Downloads
APL-1082
Drug-Linker Conjugates
APL-1082 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis. It comprises Exatecan, an effective payload, linked with a suitable spacer to enhance tumor-targeting capabilities. This compound is essential for research focused on developing targeted cancer therapies and optimizing ADC formulations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2921735-93-3 |
| Applications | Drug-Linker Conjugates |
| Formula | C60H70FN11O16 |
| Molecular Weight | 1220.26 |
| Synonyms | Mc-exo-EVC-Exatecan |
| SMILES | O=C(C=CC1=O)N1CCCCCNC(C(C2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)OC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.