Fig. 1 · Structure
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Aplindore
Dopamine D2 Receptor Agonist
Aplindore is a potent dopamine D2 receptor agonist, exhibiting a pKi value of 9.1. This compound is significant in the study of Parkinson's disease, as it aids in elucidating dopaminergic signaling pathways. Its activity provides valuable insights into therapeutic strategies for managing symptoms associated with dopaminergic deficits.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 189681-70-7 |
| Applications | Dopamine D2 Receptor Agonist |
| Formula | C18H18N2O3 |
| Molecular Weight | 310.35 |
| Synonyms | DAB-452 |
| SMILES | O=C(C1)NC2=C1C(O[C@H]3CNCC4=CC=CC=C4)=C(OC3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.