APN/AKT-IN-1 is a potent dual inhibitor targeting aminopeptidase N (APN) and protein kinase B (AKT), exhibiting IC50 values of 0.21 μM and 0.27 μM, respectively. This compound effectively blocks the phosphorylation of glycogen synthase kinase 3 beta (GSK3β), a critical substrate of AKT, thereby modulating key signaling pathways involved in cell growth, survival, and metabolism. APN/AKT-IN-1 is valuable for research applications focusing on cancer biology and therapeutic interventions targeting the APN/AKT pathway.
APN/AKT-IN-1 is a potent dual inhibitor targeting aminopeptidase N (APN) and protein kinase B (AKT), exhibiting IC50 values of 0.21 μM and 0.27 μM, respectively. This compound effectively blocks the phosphorylation of glycogen synthase kinase 3 beta (GSK3β), a critical substrate of AKT, thereby modulating key signaling pathways involved in cell growth, survival, and metabolism. APN/AKT-IN-1 is valuable for research applications focusing on cancer biology and therapeutic interventions targeting the APN/AKT pathway.
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