Apremilast (CC 10004)

Catalog No.: A11289

PDE4 Inhibitor

Apremilast (CC 10004)

Apremilast (CC 10004) Chemical Structure

CAS NO. 608141-41-9

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $40.00

Special Price $36.00

5 mg

Regular Price: $60.00

Special Price $54.00

10 mg

Regular Price: $90.00

Special Price $81.00

25 mg

Regular Price: $120.00

Special Price $108.00

200 mg
$450.00
10mM * 1mL in DMSO

Regular Price: $65.00

Special Price $58.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.
In vitro (25°C) DMSO 92 mg/mL (199.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.72 mL 108.58 mL 217.16 mL
0.5 mM 4.34 mL 21.72 mL 43.43 mL
1 mM 2.17 mL 10.86 mL 21.72 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11289
Actions Inhibitor
M. Wt 460.5
Formula C22H24N2O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 608141-41-9
Synonyms CC10004, CC-10004
SMILES CCOC1=C(C=CC(=C1)[[email protected]@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC

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