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Apremilast (CC 10004)

Apremilast (CC 10004)

Name: Apremilast (CC 10004)
Brand: Adooq Bioscience
SKU: A11289
Rating: 100 (268 reviews)

Catalog No.: A11289

PDE4 Inhibitor

Apremilast (CC 10004) Chemical Structure

CAS NO. 608141-41-9

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.

Availability: In stock

Package	Price	Qty
5 mg	$45.00
10 mg	$65.00
25 mg	$75.00
200 mg	$300.00
10mM * 1mL in DMSO	$60.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

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Biological Activity

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.

Solubility *

In vitro (25°C)	DMSO	85 mg/mL (184.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.72 mL	108.58 mL	217.16 mL
0.5 mM	4.34 mL	21.72 mL	43.43 mL
1 mM	2.17 mL	10.86 mL	21.72 mL
5 mM	0.43 mL	2.17 mL	4.34 mL

*The above data is based on the productmolecular weight 460.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11289
Actions	Inhibitor
CAS No.	608141-41-9
Formula	C22H24N2O7S
M. Wt	460.5
Purity	>98%
Synonyms	CC10004, CC-10004
SMILES	CCOC1=C(C=CC(=C1)[[email protected]@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.