Fig. 1 · Structure

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APS6-45

Tumor-calibrated Inhibitor

APS6-45 is an orally active tumor-calibrated inhibitor that selectively targets RAS/MAPK signaling pathways. It demonstrates significant antitumor activity, making it a valuable tool for cancer research and therapeutic development. This compound is particularly useful in studies aimed at understanding tumor dynamics and exploring targeted treatment strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2188236-41-9
Applications Tumor-calibrated Inhibitor
Formula C23H16F8N4O3
Molecular Weight 548.39
SMILES
O=C(C1=NC=CC(OC2=CC=C(C=C2)NC(NC3=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C3F)=O)=C1)NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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