Fig. 1 · Structure
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APY29
Cat. No.
A13828
CAS
1216665-49-4
IRE1α inhibitor
APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1216665-49-4 |
| Applications | IRE1α inhibitor |
| Formula | C17H16N8 |
| Molecular Weight | 332.36 |
| SMILES | C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 27 mg/mL (81.24 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.