Fig. 1 · Structure
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AqF026
AQP1 Activator
AqF026 is an activator of aquaporin 1 (AQP1), enhancing the channel activity of human AQP1 in the Xenopus laevis oocyte system. This compound significantly improves osmotic water transport across the peritoneum in mouse models of peritoneal dialysis. AqF026 is a valuable tool for investigating mechanisms related to ultrafiltration failure in peritoneal dialysis research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1021869-59-9 |
| Applications | AQP1 Activator |
| Formula | C20H19ClN2O5S |
| Molecular Weight | 434.89 |
| SMILES | O=C(C1=CC(S(=O)(NCC2=CC=CC=C2)=O)=C(C=C1NCC3=CC=CO3)Cl)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.