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AQP4 (201-220)

Encephalitogenic Epitope

AQP4 (201-220) is an encephalitogenic epitope targeting aquaporin-4 (AQP4), a crucial component implicated in autoimmune disorders. This peptide has been shown to induce experimental autoimmune encephalomyelitis (EAE), which features hallmark midline brain lesions, retinal pathology, and disruptions at the grey matter/white matter interface in the spinal cord. AQP4 serves as a key target antigen in the study of neuromyelitis optica, making AQP4 (201-220) valuable for research in demyelinating diseases and neuroinflammatory mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2104700-59-4
Applications	Encephalitogenic Epitope
Formula	C₉₇H₁₄₃N₂₇O₂₇S
Molecular Weight	2151.40
SMILES	O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N5[C@@H](CCC5)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC6=CNC=N6)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.