Fig. 1 · Structure

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AQP4 (205-215)

Neuromyelitis optica autoantigen

AQP4 (205-215) is a peptide fragment derived from Aquaporin-4 (AQP4), which serves as a key autoantigen in neuromyelitis optica (NMO). This peptide is upregulated and presented by B cells upon CD40 engagement, making it relevant for research into autoimmune inflammatory diseases of the central nervous system (CNS). AQP4 (205-215) is instrumental in studying the pathophysiology of NMO and developing therapeutic strategies targeting AQP4-related autoimmune responses.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2891466-35-4
Applications Neuromyelitis optica autoantigen
Formula C48H75N13O17S
Molecular Weight 1138.25
SMILES
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)=O)C)=O)CO)=O)CCSC)=O)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(O)=O)C)=O)CCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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