Fig. 1 · Structure
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AR-12463
Cholesterol Inhibitor
AR-12463 is a cholesterol inhibitor that targets the conversion of [14C]acetate to cholesterol. It effectively reduces elevated total cholesterol levels in rabbit serum and inhibits cholesterol incorporation into tissues. This compound serves as a valuable tool for studying atherosclerosis and related metabolic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 100557-04-8 |
| Applications | Cholesterol Inhibitor |
| Formula | C17H28N6O |
| Molecular Weight | 332.44 |
| SMILES | OCCN(CCCCC)C1=CC(N2CCCCC2)=NC3=NC=NN31 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.