Fig. 1 · Structure

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AR524

Golgi Mannosidase Inhibitor

AR524 is a potent Golgi mannosidase inhibitor, exhibiting superior inhibitory activity compared to the established transgenic inhibitor kifunensine. At a concentration of 10 μM, AR524 effectively inhibits spheroid formation in human malignant cells, demonstrating its potential utility in cancer research and therapeutic development. This compound may facilitate investigations into glycosylation processes and their role in tumor biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2568148-31-0
Applications Golgi Mannosidase Inhibitor
Formula C26H30N2O3
Molecular Weight 418.53
SMILES
COC1=CC=C(C=C1)C(C2=CC3=C(OCO3)C=C2)CCNCC4=CC=C(C=C4)N(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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