Fig. 1 · Structure
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Aramisulpride
5-HT7 Receptor Antagonist
Aramisulpride is a selective antagonist of the 5-HT7 receptor, exhibiting a Ki value of 22 nM. It also demonstrates antagonistic properties at D2 and D3 receptors, with Ki values of 140 nM and 13.9 nM, respectively. This compound is primarily utilized in psychiatric research, providing insights into the mechanisms of mood disorders and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 71675-90-6 |
| Applications | 5-HT7 Receptor Antagonist |
| Formula | C17H27N3O4S |
| Molecular Weight | 369.48 |
| Synonyms | (R)-Amisulpride; (R)-Esamisulpride; (R)-DAN 2163 |
| SMILES | O=C(NC[C@@H]1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=C(N)C=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.