Fig. 1 · Structure

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ARB-272572

PD-1/PD-L1 Inhibitor

ARB-272572 is a potent small molecule inhibitor targeting the PD-L1 pathway, exhibiting an IC50 value of 400 pM. This compound enhances antitumor immunity and shows promise in the treatment of chronic viral infections. ARB-272572 is valuable for research applications focused on cancer immunotherapy and viral infection studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2368182-63-0
Applications PD-1/PD-L1 Inhibitor
Formula C32H36N6O4
Molecular Weight 568.67
SMILES
CC1=C(C=CC=C1C2=CC=CC(NC(C3=NC=C(C=C3)CNCCO)=O)=C2C)NC(C4=CC=C(C=N4)CNCCO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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