Fig. 1 · Structure
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Arbemnifosbuvir
Non-Structural Protein 12 Interfering Drug
Arbemnifosbuvir is an interferent of the non-structural protein 12 (nsp12) associated with the nidovirus DdRp, targeting the nucleotidyltransferase (NiRAN) domain. This compound demonstrates significant activity against SARS-CoV infections, making it a valuable tool for studying the molecular mechanisms of viral replication and therapeutics in coronaviruses. Its application in research can aid in understanding the inhibition pathways and developing targeted antiviral strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1998705-63-7 |
| Applications | Non-Structural Protein 12 Interfering Drug |
| Formula | C24H33FN7O7P |
| Molecular Weight | 581.53 |
| Synonyms | AT-752 free base |
| SMILES | C[C@@]1(F)C(O)[C@@H](CO[P@](N[C@@H](C)C(OC(C)C)=O)(OC2=CC=CC=C2)=O)O[C@H]1N3C(N=C(N)N=C4NC)=C4N=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.