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ARCA

mRNA Capper

ARCA (Anti-Reverse Cap Analog) functions as a 5′-cap analogue specifically designed to modify mRNA. This reagent effectively enhances mRNA stability and translation efficiency, making it an essential tool in protein expression studies. ARCA is widely utilized in research applications involving mRNA modification and the investigation of gene expression regulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	400806-46-4
Applications	mRNA Capper
Formula	C₂₂H₃₁N₁₀O₁₈P₃
Molecular Weight	816.46
Synonyms	Anti-Reverse cap analog; m2 7,3′O GpppG
SMILES	O=C1C([N+](C)=CN2[C@H]3[C@H](O)[C@H](OC)[C@@H](COP(OP(OP(OC[C@H]4O[C@@H](N(C=N5)C6=C5C(NC(N)=N6)=O)[C@H](O)[C@@H]4O)(O)=O)(O)=O)([O-])=O)O3)=C2N=C(N)N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.