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Ardisianone

Anti-cancer Agent

Ardisianone is an alkyl benzoquinone derivative that serves as a potent anti-cancer agent, specifically targeting acute myeloid leukemia (AML) cells. Exhibiting significant antileukemic activity, Ardisianone demonstrates IC50 values of 1.87 μM and 1.67 μM against HL-60 cells at 24 hours and 48 hours, respectively. Its mechanism involves caspase-dependent apoptosis and the induction of pyroptosis, making it a valuable tool for research into therapeutic strategies for AML.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	66398-68-3
Applications	Anti-cancer Agent
Formula	C₂₄H₃₈O₅
Molecular Weight	406.56
SMILES	CCCCCCCCCCCCC[C@@H](OC(C)=O)CC(C(C(OC)=C1)=O)=CC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.