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Biological Activity
Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor.
Targets
| Thrombin | ||||
| 5-39 nM(Ki) |
| In vitro (25°C) | DMSO | 8 mg/mL (15.72 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (9.83 mM) | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.66 mL | 98.31 mL | 196.62 mL |
| 0.5 mM | 3.93 mL | 19.66 mL | 39.32 mL |
| 1 mM | 1.97 mL | 9.83 mL | 19.66 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.93 mL |
*The above data is based on the productmolecular weight 508.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11774 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 74863-84-6 |
| Formula | C23H36N6O5S |
| M. Wt | 508.6 |
| Purity | >98% |
| SMILES | C[[email protected]@H]1CCN([[email protected]](C1)C(=O)O)C(=O)[[email protected]](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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