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Argyrin F

Antitumoral Agent

Argyrin F is a cyclic peptide that functions as an antitumoral agent. It inhibits cell proliferation, migration, invasion, and colony formation through mechanisms that include partial apoptosis induction and modulation of epithelial-mesenchymal transition (EMT). Additionally, Argyrin F stabilizes p27kip, up-regulates p21waf1/cip1, and depletes COX2, making it a valuable tool for research on pancreatic ductal adenocarcinoma (PDAC).

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	444300-74-7
Applications	Antitumoral Agent
Formula	C₄₀H₄₄N₁₀O₉S
Molecular Weight	840.90
SMILES	COC1=C2C(C[C@@H]3NC([C@@H](NC(C4=CSC([C@H](NC(CN(C(C(NC([C@H](NC(CNC3=O)=O)C)=O)=C)=O)C)=O)CO)=N4)=O)CC5=CNC6=CC=CC=C56)=O)=CNC2=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.