Aristolactam A IIIa functions as a DYRK1A inhibitor and is derived from the alkaloid structure found in Glycosmis chlorosperma. This compound demonstrates significant inhibition of platelet aggregation induced by arachidonic acid, collagen, and platelet-activating factor. Additionally, Aristolactam A IIIa exhibits potent cytotoxic effects on HeLa cells, making it a valuable tool for research in cancer biology and cellular signaling pathways.
Aristolactam A IIIa functions as a DYRK1A inhibitor and is derived from the alkaloid structure found in Glycosmis chlorosperma. This compound demonstrates significant inhibition of platelet aggregation induced by arachidonic acid, collagen, and platelet-activating factor. Additionally, Aristolactam A IIIa exhibits potent cytotoxic effects on HeLa cells, making it a valuable tool for research in cancer biology and cellular signaling pathways.
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