Aristoquinoline

Catalog No.: A67688
nAChR Inhibitor
Aristoquinoline is a naturally occurring alkaloid derived from Aristotelia chilensis, functioning primarily as an inhibitor of the α3β4 nicotinic acetylcholine receptor (nAChR). This compound demonstrates significant biological activity by modulating neurotransmitter signaling, making it a valuable tool for research in neuropharmacology, particularly in studies related to addiction, cognitive function, and neurodegenerative diseases. Its specific inhibitory effect on nAChR presents opportunities for investigating the receptor's role in various physiological processes.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAristoquinoline is a naturally occurring alkaloid derived from Aristotelia chilensis, functioning primarily as an inhibitor of the α3β4 nicotinic acetylcholine receptor (nAChR). This compound demonstrates significant biological activity by modulating neurotransmitter signaling, making it a valuable tool for research in neuropharmacology, particularly in studies related to addiction, cognitive function, and neurodegenerative diseases. Its specific inhibitory effect on nAChR presents opportunities for investigating the receptor's role in various physiological processes.
Product Information
Catalog NumA67688
FormulaC20H24N2
Molecular Weight292.42
CAS Number2720562-34-3
SMILESCC([C@H]1C[C@@H]2C(C)=CC1)(C)N[C@H]2C3=CC=NC4=C3C=CC=C4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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