Fig. 1 · Structure
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ARN 077 (enantiomer)
NAAA Inhibitor
ARN 077 (enantiomer) is a selective inhibitor of the hydrolase enzyme N-acyl-ethanolamine acid amidase (NAAA), exhibiting an IC50 value of 3.53 μM in rat models. This compound plays a significant role in modulating endocannabinoid signaling, making it valuable for research in pain management and inflammation. Its potential applications include exploring the therapeutic effects of NAAA inhibition in various biological systems and disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1439366-88-7 |
| Applications | NAAA Inhibitor |
| Formula | C16H21NO4 |
| Molecular Weight | 291.34 |
| Synonyms | URB913 (enantiomer) |
| SMILES | O=C(OCCCCCC1=CC=CC=C1)N[C@H]2[C@H](OC2=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.