Fig. 1 · Structure
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ARN19689
NAAA Inhibitor
ARN19689 is a potent and selective non-covalent inhibitor of N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), exhibiting an IC50 of 42 nM. This compound serves as a valuable pharmacological tool for exploring its role in inflammatory conditions, providing insights into potential therapeutic interventions. Its oral bioactivity enhances its utility in preclinical research focused on pain and inflammation modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2320521-34-2 |
| Applications | NAAA Inhibitor |
| Formula | C19H27N5O4S |
| Molecular Weight | 421.51 |
| SMILES | O=S(N1[C@@H]2C[C@H](C[C@H]1CC2)OC3=NC=C(COCC)N=C3)(C4=C(C)NN=C4C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.