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Aromatase-IN-4

Aromatase Inhibitor

Aromatase-IN-4 is a potent aromatase inhibitor that effectively reduces estrogen production. It demonstrates significant anticancer activity against various cell lines, with GI50 values of 2.95 μM for MDAMB-231, 3.35 μM for MCF-7, 2.27 μM for A-549, 8.46 nM for NCI-H23, and 1.56 μM for A-498. This compound is valuable for research into hormone-dependent cancers and the role of estrogen in tumor growth.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3060588-16-8
Applications	Aromatase Inhibitor
Formula	C₂₃H₁₈N₆
Molecular Weight	378.43
SMILES	C1(NC2=NC=C(NC3=CC=C(C4=NC5=C(N4)C=CC=C5)C=C3)C=C2)=CC=CN=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.