Fig. 1 · Structure
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ART615
Isomer of ART558
ART615 is a chemical isomer of ART558 and functions as an inactive control in experiments assessing the activity of ART558. It demonstrates less than 10% inhibition of polymerase theta (Polθ) at a concentration of 12 µM, making it a suitable reagent for comparative studies involving Polθ inhibition. This compound is valuable for research applications aimed at understanding the specific mechanisms of action of ART558 in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3031765-75-7 |
| Applications | Isomer of ART558 |
| Formula | C21H21F3N4O2 |
| Molecular Weight | 418.41 |
| SMILES | O=C([C@@H]1N(C2=NC(C)=CC(C(F)(F)F)=C2C#N)C[C@H](O)C1)N(C)C3=CC=CC(C)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.