AS19 is a highly potent and selective agonist of the 5-HT7 receptor, with an IC50 value of 0.83 nM and a Ki of 0.6 nM. It demonstrates significant selectivity over other serotonin receptors, including 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A, with Kis values ranging from 6.6 nM to 490 nM. AS19 has been shown to enhance memory consolidation and effectively reverse amnesia induced by Scopolamine or Dizocilpine, making it a valuable tool for research in cognitive function and neuropharmacology.
AS19 is a highly potent and selective agonist of the 5-HT7 receptor, with an IC50 value of 0.83 nM and a Ki of 0.6 nM. It demonstrates significant selectivity over other serotonin receptors, including 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A, with Kis values ranging from 6.6 nM to 490 nM. AS19 has been shown to enhance memory consolidation and effectively reverse amnesia induced by Scopolamine or Dizocilpine, making it a valuable tool for research in cognitive function and neuropharmacology.
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