Fig. 1 · Structure

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Asarinin

Cat. No. A14746 CAS 133-05-1
Asarinin was isolated from the radix of Asiasarum heterotropoides var.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
HepG2 EC50 > 60 μM Transactivation of PPAR expressed in HepG2 cells after 20 hrs by luminescence assay [PMID: 22381047]
HepG2 IC50 7.1 μM Inhibition of TNFalpha-induced NFkappaB transcriptional activity in human HepG2 cells pretreated for 1 hr before TNFalpha challenge by luciferase reporter gene analysis [PMID: 22381047]
NIH3T3 IC50 0.2 μM Cytotoxicity against murine 3T3 cells by MTT assay [PMID: 17253847]

Specifications

Manufacturer Adooq Bioscience
CAS Number 133-05-1
Formula C20H18O6
Molecular Weight 354.35
Synonyms (-)-Asarinin
SMILES
C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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