Fig. 1 · Structure
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ASC-69
PD-1/PD-L1 Inhibitor
ASC-69 is a potent inhibitor of the PD-1/PD-L1 pathway, which plays a critical role in immune evasion by tumors. This small-molecule compound demonstrates strong biological activity in inhibiting the interaction between PD-1 and PD-L1, thereby enhancing T-cell responses against cancer cells. ASC-69 is relevant for research applications focused on cancer immunotherapy and the modulation of immune checkpoint mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1216665-50-7 |
| Applications | PD-1/PD-L1 Inhibitor |
| Formula | C19H19N7 |
| Molecular Weight | 345.40 |
| Synonyms | APY69 |
| SMILES | N#CCC1=CC=C(NC2=NC(C)=CC(NC3=NNC(C4CC4)=C3)=N2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.