Fig. 1 · Structure
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ASIC-IN-1
Acid Sensing Ion Channel Inhibitor
ASIC-IN-1 is a potent inhibitor of acid-sensing ion channels (ASICs), exhibiting an IC50 value of less than 10 µM. This compound effectively reduces pain intensity in a dose-dependent manner, making it a valuable tool for studying pain mechanisms and neurobiology. ASIC-IN-1 is particularly useful in research focused on pain signaling pathways and the modulation of nociceptive responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 308088-10-0 |
| Applications | Acid Sensing Ion Channel Inhibitor |
| Formula | C23H25N3O2 |
| Molecular Weight | 375.46 |
| SMILES | CC1=NC2=CC=CC=C2C(N3CCN(CC(C4=CC=C(OC)C=C4)=O)CC3)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.