ASK1-IN-3 is a selective inhibitor of the apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 33.8 nM. This compound demonstrates significant apoptotic induction in HepG2 cancer cells and exhibits effective cell cycle arrest. Its ability to modulate the activity of several cell cycle regulating kinases renders ASK1-IN-3 valuable for research applications related to cancer therapy and cell cycle regulation studies.
ASK1-IN-3 is a selective inhibitor of the apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 33.8 nM. This compound demonstrates significant apoptotic induction in HepG2 cancer cells and exhibits effective cell cycle arrest. Its ability to modulate the activity of several cell cycle regulating kinases renders ASK1-IN-3 valuable for research applications related to cancer therapy and cell cycle regulation studies.
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