Fig. 1 · Structure
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ASN06917370
GPR17 ligand
ASN06917370 is a potent ligand for the GPR17 receptor, which plays a critical role in the signaling pathways associated with neurodegenerative diseases. With an EC50 of 268 pM in [35S]GTPyS assays, it facilitates insights into GPR17-related biological processes. This compound is valuable for research applications focused on neurobiology and the pharmacological modulation of neurodegeneration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 837404-68-9 |
| Applications | GPR17 ligand |
| Formula | C24H21ClF3N7O2 |
| Molecular Weight | 531.92 |
| SMILES | O=C(N1CCC(C2=NC3=C(N=NN3CC4=CC=CC=C4Cl)C(N2)=O)CC1)NC5=CC=C(C(F)(F)F)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.