ASP2453

Name: ASP2453
Brand: Adooq Bioscience
SKU: A24795
Rating: 5 (288 reviews)

Catalog No.: A24795

Ras Inhibitor

ASP2453 is a selective and orally bioavailable inhibitor targeting the KRAS G12C mutation. It functions by inhibiting the interaction between KRAS G12C and Raf mediated by Son of Sevenless (SOS), demonstrating an IC50 value of 40 nM. ASP2453 shows potential in cancer research, particularly in studies addressing KRAS-driven malignancies.

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Grouped product items
Size	Price	Stock
1mg	$95.00	In stock
5mg	$245.00	In stock
10mg	$375.00	In stock
25mg	$585.00	In stock
50mg	$770.00	In stock
100mg	$2,030.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	ASP2453 is a selective and orally bioavailable inhibitor targeting the KRAS G12C mutation. It functions by inhibiting the interaction between KRAS G12C and Raf mediated by Son of Sevenless (SOS), demonstrating an IC50 value of 40 nM. ASP2453 shows potential in cancer research, particularly in studies addressing KRAS-driven malignancies.

Product Information

Catalog Num	A24795
Formula	C40H48F3N7O4
Molecular Weight	747.85
CAS Number	2241719-73-1
SMILES	C=CC(N1CC2(CCN(C3=C4C=C(C5CC5)C(C6=C(C)C=CC7=C6C=NN7)=C(OCC(F)(F)F)C4=NC(OC8CCN(CCCOC)CC8)=N3)CC2)C1)=O

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