Fig. 1 · Structure

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Aspergillusidone F

Aromatase Inhibitor

Aspergillusidone F is a brominated depsidone that functions as an aromatase inhibitor, exhibiting an IC50 of 0.5 μM. This compound has demonstrated significant cytotoxic effects against cancer cell lines, including MOLT-3 cells, highlighting its potential in cancer research. It can be isolated from the fungus Aspergillus unguis cultured in KBr medium and may provide valuable insights in studies related to breast cancer and other hormone-dependent malignancies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1558007-47-8
Applications Aromatase Inhibitor
Formula C19H16Br2O5
Molecular Weight 484.14
SMILES
C/C=C(C1=C2C(OC(C3=C(C)C=C(O)C(Br)=C3O2)=O)=C(C(O)=C1Br)C)\C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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