Fig. 1 · Structure

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AST5902

Anticancer Agent

AST5902 is an active metabolite of Firmonertinib, functioning as an inhibitor of the epidermal growth factor receptor (EGFR). This compound exhibits significant antineoplastic activity, making it a valuable tool in cancer research. Its mechanism of action targets tumor cell proliferation and survival, aiding in the exploration of therapeutic strategies against EGFR-driven malignancies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2412155-74-7
Applications Anticancer Agent
Formula C27H29F3N8O2
Molecular Weight 554.57
SMILES
C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(C)CCNC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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