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Astegolimab
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody designed to inhibit IL-33 signaling through specific binding to ST2, the receptor for IL-33. This antibody is primarily explored for its therapeutic potential in studies related to chronic obstructive pulmonary disease (COPD), offering a targeted approach to modulate immune responses implicated in this condition.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2173054-79-8 |
| Molecular Weight | 144980 |
| Synonyms | MSTT 1041A; RG 6149 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.