Astepatide

Catalog No.: A33785
GIP/GLP-1 Agonist
Astepatide is a dual agonist of the gastric inhibitory peptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor, which primarily influences glucose metabolism and insulin secretion. This compound demonstrates significant anti-diabetic activity, making it a valuable tool for research related to diabetes and metabolic disorders. Astepatide can aid in exploring mechanisms of action and therapeutic potential for obesity and type 2 diabetes.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAstepatide is a dual agonist of the gastric inhibitory peptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor, which primarily influences glucose metabolism and insulin secretion. This compound demonstrates significant anti-diabetic activity, making it a valuable tool for research related to diabetes and metabolic disorders. Astepatide can aid in exploring mechanisms of action and therapeutic potential for obesity and type 2 diabetes.
Product Information
Catalog NumA33785
FormulaC226H348N50O68
Molecular Weight4853.48
CAS Number2959444-13-2
SequenceTyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Leu-Leu-Glu-Lys-{Lys-Lys-γGlu-C18 diacid}-Gln-Ala-Ala-Arg-Glu-Phe-Ile-Glu-Trp-Leu-Leu-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser
Sequence shorteningY-{Aib}-EGTFTSDYSILLEK-{Lys-Lys-γGlu-C18 diacid}-QAAREFIEWLLAGGPSSGAPPPS
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