Fig. 1 · Structure
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AT-112
Ketanserin
AT-112 is a ketanserin analogue that primarily targets serotonin receptors. It demonstrates notable hemodynamic effects, significantly reducing blood flow in the portal vein branches and lowering portal vein pressure. This compound is valuable for investigating the pathogenesis of portal hypertension and exploring therapeutic strategies related to vascular regulation and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 139047-55-5 |
| Applications | Ketanserin |
| Formula | C21H23N5O |
| Molecular Weight | 361.44 |
| SMILES | O=C1NC2=C(C=CC=C2)C3=NC(CN4CCN(C5=CC=CC=C5)CC4)CN13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.