Fig. 1 · Structure
Documents & Downloads
AT1R antagonist 1
AT1R Antagonist
AT1R Antagonist 1 is a selective ligand targeting the angiotensin II type 1 receptor (AT1R). This compound demonstrates significant biological activity with an affinity of Ki 8.5 nM, making it an effective agent for research involving cardiovascular and hypertensive disorders. It is suitable for studies investigating the modulation of the renin-angiotensin system and exploring therapeutic pathways in related pathologies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2848719-80-0 |
| Applications | AT1R Antagonist |
| Formula | C28H32F3N5O4S2 |
| Molecular Weight | 623.71 |
| SMILES | CCCC1=NC(C2=CC=C(C=C2)CN3C(CC)=NC4=C3N=C(C=C4C)C)=C(S1)S(=O)(NC(OCCCC(F)(F)F)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.