Fig. 1 · Structure

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AT1R antagonist 2

AT1R Antagonist

AT1R Antagonist 2 is a selective antagonist of the angiotensin II type 1 receptor (AT1R). This compound demonstrates a moderate affinity for AT1R, with a Ki value of 26 nM. It is primarily utilized in research focused on cardiovascular diseases, hypertension, and related signaling pathways, making it a valuable tool for understanding AT1R-mediated physiological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2848719-76-4
Applications AT1R Antagonist
Formula C29H37N5O4S2
Molecular Weight 583.77
SMILES
CCCCOC(NS(=O)(C1=C(N=C(S1)CC(C)C)C2=CC=C(C=C2)CN3C(CC)=NC4=C3N=C(C=C4C)C)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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