AT7519

Name: AT7519
Brand: Adooq Bioscience
SKU: A10093
Rating: 5 (1 reviews)

Catalog No.: A10093

CDK Inhibitor

Adooq's AT7519 has been cited by 1 publications

AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.

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Grouped product items
Size	Price	Stock
5mg	$45.00	In stock
10mg	$70.00	In stock
25mg	$105.00	In stock
50mg	$160.00	In stock
100mg	$220.00	In stock
*10mM 1mL in DMSO**	$45.00	In stock
Bulk Size	Bulk Discount

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Research use only. We do not sell to patients.

Data Sheet SDS

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Adooq Products cited in reputable paper

Adooq's AT7519 has been cited by 1 publications

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Biological Activity

Description

AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A10093
Formula	C16H17Cl2N5O2
Molecular Weight	382.2
CAS Number	844442-38-2
SMILES	C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	9 mg/mL (23.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.16 mL	130.82 mL	261.64 mL
0.5 mM	5.23 mL	26.16 mL	52.33 mL
1 mM	2.62 mL	13.08 mL	26.16 mL
5 mM	0.52 mL	2.62 mL	5.23 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂