Atazanavir-d24 is a deuterium-labeled derivative of Atazanavir, which primarily functions as a selective and orally bioavailable HIV-1 protease inhibitor. This compound also exhibits inhibitory effects on CYP3A4 and P-glycoprotein, making it relevant for studies on drug metabolism and transport. Additionally, Atazanavir demonstrates antiviral activity against SARS-CoV 3CLpro with an IC50 of 3.49 μM and has been implicated in the inhibition of cardiac fibrosis and hyperlipidemia, as well as the induction of cell death in malignant glioma. It serves as a valuable research tool for investigating HIV treatment and related pathophysiological mechanisms.
Atazanavir-d24 is a deuterium-labeled derivative of Atazanavir, which primarily functions as a selective and orally bioavailable HIV-1 protease inhibitor. This compound also exhibits inhibitory effects on CYP3A4 and P-glycoprotein, making it relevant for studies on drug metabolism and transport. Additionally, Atazanavir demonstrates antiviral activity against SARS-CoV 3CLpro with an IC50 of 3.49 μM and has been implicated in the inhibition of cardiac fibrosis and hyperlipidemia, as well as the induction of cell death in malignant glioma. It serves as a valuable research tool for investigating HIV treatment and related pathophysiological mechanisms.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
