Fig. 1 · Structure
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ATB-343
H2S Donor
ATB-343 is a derivative of Indomethacin that functions as a hydrogen sulfide (H2S) donor. H2S demonstrates cytoprotective and anti-inflammatory properties by inhibiting leukocyte adhesion to vascular endothelium and reducing leukocyte migration to sites of inflammation. This compound is particularly useful for investigating its potential in suppressing respiratory infections and related inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1000700-26-4 |
| Applications | H2S Donor |
| Formula | C28H20ClNO4S3 |
| Molecular Weight | 566.11 |
| SMILES | O=C(CC1=C(C)N(C(C2=CC=C(C=C2)Cl)=O)C3=C1C=C(C=C3)OC)OC4=CC=C(C(SS5)=CC5=S)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.