Fig. 1 · Structure
Documents & Downloads
ATC0065 free base
MCHR1 Antagonist
ATC0065 free base is a selective antagonist of the melanin-concentrating hormone receptor 1 (MCHR1), exhibiting an IC50 of 15.7 nM against human MCHR1. This compound shows minimal activity toward MCHR2, making it a specific tool for investigating MCHR1-related pathways. ATC0065 free base demonstrates anxiolytic and antidepressant properties, making it a valuable reagent for preclinical research into mood disorders and anxiety-related conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 509145-82-8 |
| Applications | MCHR1 Antagonist |
| Formula | C25H29BrF3N5O |
| Molecular Weight | 552.43 |
| SMILES | CN(C1=NC(N[C@H]2CC[C@H](CC2)NCCC3=C(C=C(C=C3)Br)OC(F)(F)F)=NC4=C1C=CC=C4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.