Fig. 1 · Structure

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Atesidorsen sodium

GHR Inhibitor

Atesidorsen sodium is an antisense oligomer that functions as a selective inhibitor of human growth hormone receptor (GHR) mRNA translation. By targeting GHR, this reagent reduces its expression, impacting growth and metabolism pathways. It is primarily utilized in research focused on elucidating the role of GHR in various diseases and understanding growth hormone signaling mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1826859-79-3
Applications GHR Inhibitor
Molecular Weight 7164 (free acid)
Synonyms COR-004 sodium; ATL1103 sodium; ISIS 227452 sodium

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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