Fig. 1 · Structure

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Atesidorsen

GHR Inhibitor

Atesidorsen is a second-generation antisense oligomer that specifically inhibits the translation of human growth hormone receptor (GHR) mRNA. This selective inhibition effectively reduces GHR expression, leading to decreased signaling pathways associated with growth hormone activity. Atesidorsen is primarily utilized in research focused on growth hormone regulation and its implications in various metabolic disorders and conditions related to abnormal growth patterns.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 872063-57-5
Applications GHR Inhibitor
Molecular Weight 7164.00
Synonyms COR-004; ATL1103; ISIS 227452

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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